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Difference Between PTT and APTT

Difference Between PTT and APTT

Do you ever get confused when answering questions about the difference between PTT and APTT tests? If so, then this blog post is for you! We’ll dive into the main similarities and differences between these two blood clotting tests. You’ll learn what each one measure, why such a distinction exists, as well as common uses of both. By the end of this article, you should have a comprehensive understanding of what sets these two apart from one another. So keep reading to find out more!

What is PTT?

PTT, or Partial Thromboplastin Time, is a test that is used to evaluate the overall efficiency of the blood clotting process. PTT typically measures how quickly a patient’s blood forms clots, as well as how effectively those clots dissolve thereafter. This test is ordinarily conducted by taking a blood sample and allowing it to sit; during this time, PTT will measure the integrity of smaller components in the sample’s plasma. Ultimately, PTT allows medical professionals to understand any irregularities that could be impacting a patient’s ability to form stable clots in their bloodstream. In other words, it helps us gain an understanding of what might be causing potential issues with bleeding and clotting disorders.

What is APTT?

APTT, also known as Activated Partial Thromboplastin Time, is an important medical test that can provide doctors and other healthcare professionals with invaluable information about a person’s clotting abilities. APTT works by monitoring how quickly or slowly a person’s blood can form a clot. It is used to diagnose or rule out issues with the coagulation process of the body which may be cause for concern. APTT results are most commonly used to diagnose thrombotic disorders, like deep vein thrombosis, as well as conditions like hemophilia that make it difficult for a person to form clots properly. It is an essential tool in managing bleeding and certain clotting-related illnesses.

Difference Between PTT and APTT

  • PTT and APTT are two blood tests that measure different aspects of the blood system. PTT (Partial Thromboplastin Time) is a test which measures how long it takes for the body to form clots, which are necessary for proper wound healing.
  • APTT (Activated Partial Thromboplastin Time) is a higher-level test than PTT, assessing the coagulation time when certain substances, such as heparin or other clotting factors, have been added to the sample.
  • Both PTT and APTT help doctors ascertain if there is an issue with clot formation in the patient’s blood; however, PTT helps identify issues involving the intrinsic pathway of clotting and APTT evaluates whether or not external factors or components are impacting blood-clotting ability.


The difference between PTT and APTT is that PTT measures how long it takes for clotting factors to activate, while APTT measures the time it takes for a clot to form once all the clotting factors have been activated. While both tests are used to assess blood clotting, they provide different information about a person’s ability to form clots. APTT is more sensitive to defects in the early steps of the clotting process, while PPT is more sensitive to defects in later steps. Because of this, APTT is generally more useful in diagnosing problems with blood clotting.

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