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Difference between Polypeptide and Protein

Difference between Polypeptide and Protein

Polypeptides and proteins are two important biological molecules. Though they share some common features, they have unique characteristics that set them apart. In this article, we will explore the difference between polypeptides and proteins and discuss their importance in the body. We will also discuss how they are made and what happens when they are broken down. Keep reading to learn more!

What is Polypeptide?

  • Polypeptides are long-chain molecules made up of smaller units called amino acids. Polypeptides can be found in all living organisms, and they play a vital role in many biological processes, such as cell signaling and communication, metabolism, and transportation. Polypeptides vary in length, depending on the number of amino acids that they contain.
  • Some polypeptides, such as enzymes, can be quite large, while others, such as hormones, are much smaller. Polypeptides can be further classified based on their structure and function.
  • For example, ribosomal RNA is a type of polypeptide that helps to assemble proteins within cells. Transfer RNA is another type of polypeptide that helps to deliver amino acids to the site of protein synthesis. Polypeptides play a vital role in the function of cells and the overall health of an organism.

What is Protein?

Protein is a essential nutrient that helps the body to grow and repair itself. It is made up of amino acids, which are the building blocks of cells. Protein can be found in food such as meat, fish, eggs, dairy, beans, and nuts. It is also available in powder form. Protein is important for muscles, bones, skin, and hair. It is also needed for the body to make enzymes and hormones. Most people need about 0.36 grams of protein per pound of body weight per day. athletes and people who are recovering from an injury may need more protein. Too much protein can be harmful to the kidneys.

Difference between Polypeptide and Protein

  • Polypeptides and proteins are both macromolecules that are essential for the function of all living things. Polypeptides are made up of smaller units called amino acids, which are joined together by peptide bonds. Proteins, on the other hand, are composed of one or more polypeptides that have been folded into a specific three-dimensional shape.
  • This shape is determined by the sequence of amino acids in the Polypeptide. Proteins play a variety of roles in the body, including enzymatic activity, cell signaling, and transport.
  • Polypeptides, while not as functionally diverse as proteins, are involved in a number of important processes, such as metabolism and cell division. In general, proteins are more complex molecules than Polypeptides.


We’ve learned that proteins are made up of amino acids and polypeptides are chains of amino acids. Proteins play a vital role in the body, while polypeptides do not have as many functions. The main difference between proteins and polypeptides is that proteins can be digested while polypeptides cannot.

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