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Difference between Lysosome and Peroxisome

Difference between Lysosome and Peroxisome

In biology, a lysosome is a cellular organelle that contains hydrolytic enzymes. The primary function of lysosomes is to digest various kinds of macromolecules in the cytoplasm, including proteins, lipids, and nucleic acids. Contrastingly, peroxisomes are organelles in eukaryotic cells that primarily catalyze the breakdown of hydrogen peroxide into water and oxygen gas. This blog post will explore the difference between these two organelles.

What is Lysosome?

Lysosomes are organelles that carry out lysing or breaking down, of various materials in a cell. Lysing is achieved by Lysosome’s digestion enzymes. Lysosomes break down food particles, unused cell parts, and material from the cell’s surface.

  • Lysosomal enzymes are also responsible for getting rid of pathogens, such as bacteria, that enter the cell. Lysosomes are membrane-bound sacs that contain these digestive enzymes.
  • Lysosomes are found in all types of cells, including plant and animal cells. Lysosomes vary in size depending on the type of cell they are in. Lysosomes were first discovered in 1967 by Christian de Duve.
  • Lysosomal enzymes are important because they help to keep cells functioning properly. If lysosomal enzymes are not working correctly, it can lead to diseases, such as Tay-Sachs disease.

What is Peroxisome?

Peroxisomes are organelles that are found in the vast majority of eukaryotic cells. These organelles play an important role in cell metabolism, and they are particularly important for the breakdown of Fatty acids and Peroxides.

  • Peroxisomes are generally spherical in shape, and they range in size from about 0.1 to 1.0 micrometers. These organelles contain a variety of enzymes, including catalase, which helps to convert Hydrogen Peroxide into water and oxygen.
  • Peroxisomes also play a role in the synthesis of lipids, such as lecithin and cholesterol. In addition, they help to detoxify certain xenobiotics, such as alcohol and phenols.
  • Although the exact function of peroxisomes varies depending on the cell type, these organelles are essential for the proper functioning of eukaryotic cells.

Difference between Lysosome and Peroxisome

Lysosome and peroxisome are organelles present in the cells of eukaryotic organisms. Both of them have unique functions which are essential for the cell.

  • Lysosomes are responsible for the breakdown and recycling of cellular components, while peroxisomes are involved in detoxification and lipid metabolism. Although both organelles share some similarities, there are also several differences between them.
  • Lysosomes are spherical in shape, while peroxisomes are usually kidney-shaped. Lysosomes also have a thicker membrane as compared to peroxisomes.
  • Lysosomes contain hydrolytic enzymes that break down macromolecules, while peroxisomes contain enzymes that catalyze oxidation reactions. Peroxisomes also have the ability to produce hydrogen peroxide, which is used in various cellular processes.

Thus, lysosome and peroxisome are two different organelles with distinct functions. While lysosomes help in decomposition, peroxisomes play an important role in metabolic processes.


Lysosomes and peroxisomes are both organelles found in cells, but they have different functions. Lysosomes are responsible for breaking down proteins and other cellular components, while peroxisomes are responsible for destroying toxins and converting food into energy. Understanding the difference between these two organelles is important for understanding how cells work and can be helpful in diagnosing diseases.

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