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Difference between ITP and TTP

Difference between ITP and TTP

There is a big difference between ITP and TTP, two very different blood diseases. ITP is an autoimmune disease where the body attacks its own platelets, while TTP is a rare blood disorder caused by a lack of plasminogen activator. Each disease has unique symptoms and requires different treatments. Knowing the differences between these diseases is important for anyone affected by them or who knows someone with one of these conditions.

What is ITP?

ITP is a short-term disorder that results in the destruction of platelets, which are necessary for blood clotting. ITP can occur on its own or as a result of another condition, such as cancer or HIV. ITP typically causes bleeding from the gums or nose and easy bruising. In severe cases, ITP can lead to internal bleeding. ITP is usually treated with medications, such as corticosteroids or immune globulin. In some cases, ITP may require more aggressive treatment, such as splenectomy. ITP is a serious condition, but it is usually treatable.

What is TTP?

  • TTP is a potentially fatal blood disorder that can result in the formation of blood clots. The condition is caused by a deficiency of a protein called von Willebrand factor, which helps to keep the blood clotting.
  • TTP can cause a wide range of symptoms, including fatigue, bruises, and nosebleeds. In severe cases, TTP can lead to stroke or heart attack.
  • While there is no cure for TTP, treatment typically involves the use of medication to help manage the condition. With proper treatment, most people with TTP are able to live relatively normal lives. However, TTP can be a serious condition, and it is important to seek medical attention if you think you may have the condition.

Difference between ITP and TTP

ITP and TTP can both be used to diagnose and treat different conditions. ITP is a blood disorder that causes low platelet counts. TTP is a rare blood condition that can lead to low platelet counts and serious organ damage.

  • ITP can be treated with medications, while TTP requires plasma transfusions. ITP can also occur spontaneously, while TTP usually occurs after an infection or illness. ITP is more common in children, while TTP is more common in adults.
  • ITP can usually be managed with lifestyle changes and medication, while TTP often requires hospitalization. ITP can lead to easy bruising and bleeding, while TTP can cause organ failure and death.
  • Early diagnosis and treatment of ITP are important to prevent serious complications. Early diagnosis and treatment of TTP is also important to prevent serious complications.


Although both ITP and TTP are blood disorders, they have different causes and treatments. If you are experiencing symptoms of either disorder, it is important to see a doctor right away for diagnosis and treatment.

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