difference between z

Difference between Constitutional Isomers and Stereoisomers

Difference between Constitutional Isomers and Stereoisomers

It can be tricky to tell the difference between constitutional isomers and stereoisomers. But, understanding this distinction is essential for chemists who are synthesizing new molecules or pharmacists creating medicines. In this blog post, we’ll break down what exactly makes these two structural forms different from one another and provide examples of both types of compounds so you can see how they differ on an atomic level. With this knowledge in mind, it will be easier for scientists to determine how certain structures affect the physical and chemical properties of a substance as well as its potential utility. Read on to learn more about constitutional isomers and stereoisomers!

What are Constitutional Isomers?

Constitutional Isomers are a type of molecular structure where the same atoms are used to create different molecules. While the atomic components remain the same, Constitutional Isomers differ in how their bonding patterns and arrangements affect the overall shape of their molecules. This is especially notable for organic molecules which feature different functional groups that yield diverse chemical properties. Constitutional Isomers are important because they illustrate critical differences between how molecules behave in chemical reactions, even though they contain the same main elements. Constitutional Isomers are valuable when examining biochemical pathways or designing new medicinal compounds.

What are Stereoisomers?

  • Stereoisomers are a type of isomer molecules that have the same molecular formula but differ in the arrangement of their atoms in space. Stereoisomers can be further divided into two categories: constitutional isomers and stereoisomers.Constitutional isomers differ in their bond connectivity while stereoisomers differ in their spacial arrangement.
  • Stereoisomerism, also known as spatial isomerism, can result from several situations such as cis-trans or E-Z isomerism where the substituents on the central atom are either on the same side or opposite sides of each other.Stereoisomers can be classified into enantiomers, diasteriomers, and epimers, depending on how closely related they are to each other.
  • Stereoisomer molecules tend to have different physical and chemical properties because of their distinct arrangement which causes them to interact differently with other molecules and react differently with different solvents. Stereoisomer molecules have many practical applications such as acting as drugs, pesticides, flavourings, and even sunscreens.

Difference between Constitutional Isomers and Stereoisomers

Constitutional Isomers and Stereoisomers have an important difference between them. Constitutional Isomers, also known as Structural Isomers, differ in the order and type of atoms present in the compound. On the other hand, Stereoisomers differ in their three-dimensional spatial arrangement regardless of their identical composition and connectivity of atoms.

Constitutional Isomerism helps scientists explore isomerization reactions which result in new features such as different boiling points or melting points compared to original compounds while Stereoisomerism enables researchers to understand configuration structures within larger molecules that possess optical activity. Understanding the differences between Constitutional Isomers and Stereoisomers can help scientists uncover properties that could not be discovered before.


Constitutional isomers are molecules that have the same molecular formula but a different connectivity of their atoms, while stereoisomers are molecules that have the same connectivity of their atoms but a different three-dimensional arrangement. These two types of isomers can be further classified into several subcategories, such as enantiomers, diastereomers, and geometric isomers. While some constitutional isomers can be converted into each other through simple bonding rearrangements, others require breaking and forming new bonds altogether. Stereoisomers, on the other hand, generally cannot be converted into each other without breaking and reforming bonds.

Share this post

Share on facebook
Share on twitter
Share on linkedin
Share on email