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Difference between Antacids and H2 Blockers

Difference between Antacids and H2 Blockers

Are you feeling nauseous or have a burning sensation in your chest? You may need to take an antacid or H2 blocker. Antacids work by neutralizing stomach acids, while H2 blockers work by blocking the production of stomach acids. Here is a closer look at the difference between antacids and H2 blockers.

What is Antacid?

Antacids are a class of drugs that are used to treat dyspepsia, heartburn, and gastroesophageal reflux disease (GERD). Antacids work by neutralizing stomach acid and increasing the pH of the stomach contents. This helps to relieve symptoms such as heartburn and indigestion. Antacids are available over-the-counter or can be prescribed by a healthcare provider. Some common side effects of antacids include constipation, diarrhea, and gas.

What is H2 Blocker?

H2 Blocker is a medication that works to reduce the amount of stomach acid produced by the body. It is typically used to treat conditions like heartburn and ulcers, and can also be used to prevent gastric acid buildup during medical procedures. H2 Blockers work by binding to histamine receptors in the stomach, which helps to reduce the production of stomach acid. These medications are available in both over-the-counter and prescription form, and their effects typically last for several hours.

Difference between Antacids and H2 Blockers

  • Antacids are a class of drugs used to relieve heartburn and indigestion by neutralizing stomach acid. H2 blockers are a class of drugs used to reduce stomach acid by blocking the action of histamine, a key player in the production of stomach acid.
  • Antacids work quickly to relieve symptoms, but their effects don’t last long. H2 blockers take longer to work, but their effects can last up to 12 hours.
  • Both antacids and H2 blockers are available over the counter and by prescription.
  • There are some potential side effects associated with both antacids and H2 blockers, including constipation, diarrhea, and headaches.
  • It’s important to speak to a doctor before taking either type of medication, as they can interact with certain medications, such as warfarin (a blood thinner) and iron supplements.


Antacids and H2 blockers are both medications used to treat heartburn and acid reflux. However, they work in different ways and have different side effects. If you are experiencing heartburn or acid reflux, speak to your doctor about which medication is right for you.

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