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Difference between AML and CML

Difference between AML and CML

Chronic myeloid leukemia (CML) and acute myeloid leukemia (AML) are two forms of leukemia that affects the blood. While they share some similarities, there are also key differences between these two types of leukemia. In this blog post, we will explore the difference between AML and CML, including the symptoms, treatment options, and prognosis. We hope this information will be helpful for those who are looking to learn more about these two forms of leukemia.

What is AML?

AML is a cancer of the blood and bone marrow. AML develops when the body produces abnormal white blood cells. These abnormal cells crowd out the normal cells in the bone marrow, and they do not function properly. AML is a type of leukemia, which is a cancer of the blood-forming tissues. AML is considered to be an acute leukemia because it progresses rapidly and can be life-threatening. AML is usually treated with chemotherapy, and sometimes with stem cell transplantation. The prognosis for AML varies depending on the patient’s age and health, but AML is generally considered to be a serious disease.

What is CML?

  • CML is a type of cancer that starts in the blood-forming cells of the bone marrow. CML develops when a gene called BCR-ABL is produced. This gene makes an abnormal protein that signals the bone marrow cells to grow and divide too quickly. CML usually progresses slowly, and most people diagnosed with CML can expect to live for years with the disease.
  • CML can sometimes transform into a more aggressive form of leukemia, however, which is why it is important to monitor the disease closely and receive treatment as soon as possible. There are several different types of treatment available for CML, including targeted therapy, chemotherapy, and stem cell transplant. The best course of treatment will vary from person to person, so it is important to work with a medical team that is experienced in treating CML. With proper treatment, CML can be managed effectively and people can enjoy a good quality of life.

Difference between AML and CML

  • AML and CML are two different types of blood cancer. AML is acute myeloid leukemia, while Cml is chronic myeloid leukemia. AML is a cancer of the blood and bone marrow, while Cml is a cancer of the white blood cells. AML is more aggressive and often fatal, while Cml is slower growing and can be treated with medication.
  • AML typically affects adults, while Cml can occur at any age. AML treatment often involves chemotherapy, while Cml treatment may involve targeted therapy or stem cell transplant. AML prognosis is generally poor, while Cml prognosis is better. AML patients have a lower survival rate than CML patients. AML and CML are both serious diseases, but they differ in many ways.


Although both diseases have some commonalities, there are also several key distinctions between AML and CML. It is important for patients and their families to be aware of these differences in order to make the best treatment decisions possible. If you or someone you love has been diagnosed with leukemia, please don’t hesitate to reach out for help. The Leukemia & Lymphoma Society provides valuable information and support services for patients and their loved ones affected by these diseases.

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